Exercise Physiology
Maryam Kafi; khadijeh irandoust
Abstract
Introduction: The aim of this study was to evaluate the importance of aerobic exercise and quercetin supplementation on the progression of colon cancer in rats and changes in the effects of IGF1 and myostatin on muscle tissue and the shape of fluctuations in atrophy and muscle wasting. Methods: The subjects ...
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Introduction: The aim of this study was to evaluate the importance of aerobic exercise and quercetin supplementation on the progression of colon cancer in rats and changes in the effects of IGF1 and myostatin on muscle tissue and the shape of fluctuations in atrophy and muscle wasting. Methods: The subjects of this study included 25 male Wistar rats (weight: 250± 30 g, age: 12 weeks) which were homogenized by weight and randomly divided into 5 groups (5 heads in each group) of healthy controls. Cancer control group, cancer group + quercetin supplement, cancer group + aerobic exercise, cancer group + quercetin supplement + aerobic exercise was evaluated. Measurements of IGF1 and myostatin in muscle tissue of rats were performed according to the standard and ELISA method. SPSS software was used for data analysis. Results: The results showed that 8 weeks of aerobic training in muscle tissue of mice with colon cancer had a significant effect on the mean values of myostatin (p = 0.005) and IGF1 (p = 0.019). 8 weeks of quercetin supplementation in muscle tissue of mice with colon cancer had a significant effect on mean myostatin and mean values IGF (P <0.05) in the control and experimental groups (8 weeks of quercetin supplementation) had no significant effect on mean myostatin and IGF1. (P>0/05) Conclusion: In general, the findings showed that aerobic exercise and quercetin supplementation improve IGF1 and reduce myostatin in muscle tissue of mice with colon cancer.
Sports and health nutrition
Bahareh Rahmani; Morteza taheri; khadijeh irandoust
Abstract
Abstract, the aim of the present study was to investigate the effect of cumin intake following partial sleep deprivation (PSD) on the oxidation of carbohydrates and fats and some cardiorespiratory indices in student-athletes.Materials and Methods: The present study was quasi-experimental and the research ...
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Abstract, the aim of the present study was to investigate the effect of cumin intake following partial sleep deprivation (PSD) on the oxidation of carbohydrates and fats and some cardiorespiratory indices in student-athletes.Materials and Methods: The present study was quasi-experimental and the research design was cross-sectional. The statistical population included all female student-athletes of Imam Khomeini International university (Age: 18-25 years), of whom 8 students were chosen based on convenience sampling method (Age: 20.01± 53 0.53; height 163.50± 6.57 cm;, weight 56.54± 2 2.54 kg; body mass index 21.19 ± 1.85 kg / m2; maximum oxygen consumption 87 58.30±5.5 kg / min and heart rate 93.63 ±5.15 beats per minute). The main group consisted of 8 subjects who were initially tested as a control group; they were then tested again as placebo and supplement groups after a seven-day wash out period, respectively. PSD was performed for 4 hours the night before the test. Exhaustion was measured and recorded by Bruce treadmill test; cardiorespiratory parameters, carbohydrate and fat oxidation were analyzed by gas analyzer. Results: The results suggested that carbohydrate oxidation increased at the time of maximum oxygen consumption (Vo2max) in the cumin supplement group (p≤0.05). Carbohydrate oxidation and respiratory exchange ratio also increased at the time of anaerobic threshold and Vo2max in cumin supplement group (p≤0.05). Conclusion: In summary, it can be said that taking cumin pills improves the performance of sleep deprived athletes.
